Mutalik, G. S. published the artcileComparative clinical trial of bitoscanate, bephenium hydroxynaphthoate, and tetrachlorethylene in hookworm infection, COA of Formula: C28H29NO4, the publication is Indian Journal of Medical Sciences (1972), 26(11), 718-22, database is CAplus and MEDLINE.
Bitoscanate (I) [4044-65-9] (200-300 mg/day) decreased fecal egg counts by 98% and cured 15 of 23 patients with hookworm whereas bephenium hydroxynaphthoate [3818-50-6] (2.4 g) decreased fecal egg count by 76% and cured 3 of 23 patients and tetrachloroethylene [127-18-4] (3 mL) decreased egg counts by 89% and cured 5 of 23 patients. Mild and transient gastrointestinal reactions were obsd with all 3 drugs but most frequently with bitoscanate.
Indian Journal of Medical Sciences published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, COA of Formula: C28H29NO4.
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