Maharvi, Ghulam M.’s team published research in Tetrahedron Letters in 51 | CAS: 2240-88-2

Maharvi, Ghulam M. published the artcileA synthesis of the γ-secretase inhibitor BMS-708163, SDS of cas: 2240-88-2, the publication is Tetrahedron Letters (2010), 51(50), 6542-6544, database is CAplus.

A concise, convergent racemic synthesis of BMS-708163 (I) was reported. Two fragments consisting of N-4-chlorophenylsulfonyl-3,3,3-trifluoropropylglycine and a 1,2,4-oxadiazole derivative of 2-fluorobenzyl alc. were prepared in sep. pots and then coupled together via a Mitsunobu reaction. Since a convenient chiral synthesis of optically pure (D)-3,3,3-trifluoropropyl glycine Me ester was developed using Schoellkopf reagent alkylation, this methodol. can also be adopted for the enantioselective synthesis of BMS-708163.

Tetrahedron Letters published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, SDS of cas: 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts