Lewinska, Agnieszka published the artcileTargeted hybrid nanocarriers as a system enhancing the skin structure, Safety of 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Molecules (2021), 26(4), 1063, database is CAplus and MEDLINE.
The skin is constantly exposed to external and internal factors that disturb its function. In this work, two nanosystems-levan nanoparticles and a surfactin-stabilized nanoemulsion were preserved (tested for microbial growth) and characterized (size, polydispersity, Zeta potential, and stability). The nanosystems were introduced in the model formulations-cream, tonic, and gel, and confirmed by TEM. The anal. showed that nanoemulsion has a spherical morphol. and size 220- 300 nm, while levan nanoparticles had irregular shapes independently of the use of matrix and with particle size (130-260 nm). Addnl., we examined the antiradical effect of levan nanoparticles and nanoemulsion in the prototype of formulations by scavenging DPPH (2,2-diphenyl-1-picrylhydrazyl; EPR spectroscopy). The model cream with both nanosystems and the whole range of products with nanosystems were evaluated in vivo for hydration, elasticity, smoothness, wrinkles and vascular lesions, discoloration, resp. The cream improved skin condition in all tested parameters in at least 50% of volunteers. The use of more comprehensive care, addnl. consisting of a tonic and gel, reduced the previously existing skin discoloration to 10.42 ± 0.58%. The presented prototype formulations are promising in improving skin conditions.
Molecules published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Safety of 3-((2-Ethylhexyl)oxy)propane-1,2-diol.
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