Hanack, M.’s team published research in Angewandte Chemie in 74 | CAS: 50915-29-2

Angewandte Chemie published new progress about 50915-29-2. 50915-29-2 belongs to alcohols-buliding-blocks, auxiliary class Cyclopropanes, name is (1-Bromocyclopropyl)methanol, and the molecular formula is C4H7BrO, SDS of cas: 50915-29-2.

Hanack, M. published the artcileStudies on cyclopropane derivatives, SDS of cas: 50915-29-2, the publication is Angewandte Chemie (1962), 116-17, database is CAplus.

Dicyclopropylcarbinol (I) (Hart and Curtis, CA 50, 12839f) with PCl5 or PCl3 at — 15° gave only 1-cyclopropyl-4-chloro-1-butene (II), b12 60-2°, in 85% yield. With 3% HCl at 80° I gave 69% II and 11% cyclopropylbutadiene (III), b. 96-7°. With AcCl in Et2O, I gave 10% acetate (IV) and 22% II. Pure IV was easily obtained with Ac2O; alk. saponification gave only I. With PBr3 in Et2O or with 60% HBr at 0° I gave only 1-cyclopropyl-4-bromo-1-butene in 80% yield. Hydrolysis of II with 10% K2CO3 3 hrs. at 80° gave 35% I. With Na amylate, II gave III, which easily formed a diene adduct, m. 84-5°, with maleic anhydride. Dicyclopropyl ketone (V) (Hart and C., loc. cit.) and MeMgI gave 70% dicyclopropylmethylcarbinol, b15 58°. With Na and EtOH the oxime of V easily gave the amine. Methylcyclopropylcarbinol (VI) with concentrated HCl and ZnCl2 at 0° gave 5-chloro-2-pentene, which gave 10% VI when hydrolyzed with 10% K2CO3 3 hrs. at 80°.

Angewandte Chemie published new progress about 50915-29-2. 50915-29-2 belongs to alcohols-buliding-blocks, auxiliary class Cyclopropanes, name is (1-Bromocyclopropyl)methanol, and the molecular formula is C4H7BrO, SDS of cas: 50915-29-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts