Ekrami, Ali published the artcileDevelopment and evaluation of Zhumeria majdae essential oil-loaded nanoliposome against multidrug-resistant clinical pathogens causing nosocomial infection, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Journal of Drug Delivery Science and Technology (2022), 103148, database is CAplus.
In this study, we used Zhumeria majdae essential oil (ZMEO) loaded nanoliposome (NLP) to control several multidrug-resistant clin. pathogens (MDRs) that cause nosocomial infections using thin-layer hydration. Initially, ZMEO was extracted and analyzed by GC-MS, and then NLP-ZMEO was examined with different ratios of ZMEO to lecithin. Based on evaluation of release profile and phys. stability, size distribution, and particle size, using dynamic light scattering (DLS) results, the most stable NLP-ZMEO were prepared from ZMEO to lecithin ratio 1:3 that relative to pure ZMEO presented more potent antioxidant, anti-quorum sensing, and anti-biofilm activities. The morphol. results (AFM and SEM) also agreed with DLS anal. Also, the results of structural properties (DSC and FTIR) approved interaction between ZMEO and NLP. Comparing the cytotoxic effect on fibroblasts cell lines and antibacterial activity (MIC, MBC, and agar disk diffusion method), it was found that the antimicrobial activity in NLP-ZMEO was higher than ZMEO against multidrug-resistant clin. pathogens that cause nosocomial infection. The subcytotoxic values of the tested NLP-ZMEO were higher than MICs and MBCs for MDR bacteria and chlorhexidine doses.
Journal of Drug Delivery Science and Technology published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol.
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