Arriaga Alba, M. published the artcileMutagenicity of urine from mice exposed orally to nitrite and various aminated antiparasitic drugs, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Environmental and Molecular Mutagenesis (1989), 14(1), 13-19, database is CAplus and MEDLINE.
The mutagenic activity of mouse urine was determined after oral administration of sodium nutrite and pyrantel pamoate, chloroquine, piperazine, dehydroemetine, iodochlorhydroxyquin, and bephenium hydroxynaphthoate. The simultaneous administration of piperazine or chloroquine with sodium nitrite produced urinary mutagens that appeared conjugated as glucuronides, whereas pyrantel pamoate and dehydroemetine in the presence of nitrite caused only slight mutagenic urine. No mutagenic activity was detected in the urine of mice to which halogenated derivatives of tertiary amines (iodochlorhydroxyquin) or quaternary ammonium salts (bephenium hydroxynaphthoate) were administered together with nitrite.
Environmental and Molecular Mutagenesis published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.
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