Barber, Amelia Moreno published the artcileSolid-phase synthesis of novel inhibitors of farnesyl transferase, Safety of (4-Butoxyphenyl)methanol, the main research area is hydroxynitrotrifluorophenyl ether preparation farnesyl transferase inhibitor.
A novel diphosphate mimic, the 2,3,6-trifluoro-5-hydroxy-4-nitrophenoxy group, has been employed as the template in the solid-phase synthesis of novel farnesyl transferase inhibitors using the Mitsunobu reaction. The most potent inhibitor 1-farnesyloxy-5-hydroxy-2,3,6-trifluoro-4-nitrobenzene displayed an IC50 of 6.3 μM vs. farnesyl transferase.
Bioorganic & Medicinal Chemistry Letters published new progress about hydroxynitrotrifluorophenyl ether preparation farnesyl transferase inhibitor. 6214-45-5 belongs to class alcohols-buliding-blocks, name is (4-Butoxyphenyl)methanol, and the molecular formula is C11H16O2, Safety of (4-Butoxyphenyl)methanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts