Akermi, Sarra published the artcileNeuroprotective effect of the essential oil of Lavandula officinalis against hydrogen peroxide-induced toxicity in mice, Product Details of C10H18O, the main research area is essential oil hydrogen peroxide Lavandula officinalis neuroprotective effect toxicity.
Brain is the main organ that manages all other organs and has significant oxygen requirements, which makes it vulnerable to reactive oxygen species, thus causing different neurol. disorders. The aim of this work is the evaluation of Lavandula officinalis essential oil neuroprotective effect against hydrogen peroxide (HP)-induced toxicity in mice. Essential oil was extracted by hydrodistillation using a Clevenger-type apparatus Essential oil anal. is performed using gas chromatog.-mass spectrometry (GC-MS). Biol. activity evaluation carried out the ferric reducing antioxidant power test, DNA (DNA) fragmentation assay, the histopathol. study of the brain, and determination of antioxidant enzyme activities. Chem. characterization of essential oil using GC-MS identified 47 compounds, accounting for almost 80% of the total oil and indicates the occurrence of monoterpenes and sesquiterpenes. The identified major compounds are pentanone (16.55%), propanal (15.89%), Me Et ketone (13.51%), naphthalene (10.81%), terpinen-4-ol (6.55%), cyclopentanecarboxylic acid (4.77%), and isoborneol (2.27%). This study allowed us to investigate the effects of HP on brain function in Mus musculus adult mice by assessing DNA degradation, cell morphol., oxidative balance and brain weight variation. Furthermore, we have highlighted the beneficial effects of L. officinalis essential oil, which could significantly counteract all these alterations by its active compounds, which are endowed with potent biol. activities. We can conclude that HP-induced damage in histomorphol. changes in mice brain, significant atrophy, as well as an important alteration of the genetic expression.
Pharmacognosy Magazine published new progress about Atrophy. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.
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