Yang, Chen published the artcileOptimation for preparation of oligosaccharides from flaxseed gum and evaluation of antioxidant and antitumor activities in vitro, Application In Synthesis of 59-23-4, the main research area is flaxseed gum oligosaccharide antioxidant antitumor activity; Antioxidant activity; Antitumor activity; Flaxseed polysaccharides; Oligosaccharides preparation.
Flaxseed oligosaccharides (FGOS) were prepared by degradation of flaxseed gum (FG) using enzymic method. Factors affecting the enzymic hydrolysis of FG were investigated by single factor and orthogonal tests. In the optimum hydrolysis conditions (reaction time 12 h, temperature 50°C, pH 4.5, cellulase concentration 100 U/mL), the reducing sugar ratio and extraction yield of FGOS were 33.6 ± 0.35% and 56.8 ± 0.41%, resp. The average mol. weight of FGOS was about 1.6 kDa, which consists of mannose, galactose, glucose, arabinose, glucuronic acid, xylose, rhamnose, ribose, galacturonic acid. Fourier-transform IR spectra and NMR indicated that FG was successfully degraded to FGOS. FGOS exhibited better antioxidant activities than FG on scavenging hydroxyl, ABTS and DPPH radicals. In vitro cytotoxicities experiments reveal FGOS acquire the ability of antiproliferation against HepG2 and Hela cells in a dose-dependent manner.
International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.
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