Sagandira, Cloudius R. published the artcileContinuous-Flow Synthesis of (-)-Oseltamivir Phosphate (Tamiflu), SDS of cas: 584-02-1, the main research area is mesylation oseltamivir phosphate Tamiflu synthesis shikimate azide.
Herein the anti-influenza drug (-)-oseltamivir phosphate is prepared in continuous flow from Et shikimate with 54% overall yield over nine steps and total residence time of 3.5 min from the individual steps. Although the procedure involved intermediate isolation, the dangerous azide chem. and intermediates involved were elegantly handled in situ. It is the first continuous-flow process for (-)-oseltamivir phosphate involving azide chem. and (-)-shikimic acid as precursor.
Synlett published new progress about Sulfonylation. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, SDS of cas: 584-02-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts