Chen, Guijie published the artcileStructural Characterization and Immunostimulatory Activity of Heteropolysaccharides from Fuzhuan Brick Tea, Synthetic Route of 59-23-4, the main research area is immunostimulatory heteropolysaccharide Fuzhuan brick tea; Fuzhuan brick tea; immunostimulatory activity; polysaccharides; structural characterization.
Fuzhuan brick tea (FBT), one of the unique dark teas, has various health-promoting functions. In the present study, one polysaccharide fraction, namely FBTPS-2-1, was extracted and purified from FBT, and its structure and potential immunostimulatory activity were investigated. The results showed that FBTPS-2-1,one of typical heteropolysaccharides, was mainly composed of Gal, Ara, and Glc with little molar content of Man, Rha, GalA, and GlcA in molar ratio of 46.59:22.13:13.57:8.20:6.02:2.12:1.38 and mol. weight of 748 kDa. The backbone of FBTPS-2-1 contained â?)-β-D-Galp-(1â?)-β-D-Galp-(1â? â?)-β-D-Galp-(1â?)-α-D-Glcp-(1â? â?)-α-D-Glcp-(1â?)-α-D-Glcp-(1â? â?)-α-D-Glcp-(1â?)-β-D-Galp-(1â? â?)-β-D-Galp-(1â?)-β-D-Galp-(1â? â?,6)-β-D-Galp-(1â?)-β-D-Galp-(1â?and â?,6)-β-D-Galp-(1â?,6)-β-D-Galp-(1â? The linkages of branches in FBTPS-2-1 were mainly composed of α-L-Araf-(1â?,6)-β-D-Galp-(1â? â?)-α-L-Araf-(1â?,6)-β-D-Galp-(1â? â?)-β-D-Galp-(1â?,6)-β-D-Galp-(1â? α-L-Araf-(1â?,5)-α-L-Araf-(1â? â?,5)-α-L-Araf-(1â?)-α-L-Araf-(1â? α-D-Galp-(1â?,5)-α-L-Araf-(1â?and â?)-α-L-Araf-(1â?)-β-D-Galp-(1â? Furthermore, FBTPS-2-1 could increase the phagocytosis of macrophages and promote the secretion of NO and a variety of inflammatory cytokines, including TNF-α, IL-1β, and IL-6, indicating noticeable immune enhancement activity. Thus, FBTPS-2-1 could serve as a potentially functional food to improve human health by modulating the host immunoreaction.
Journal of Agricultural and Food Chemistry published new progress about Homo sapiens. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.
Referemce:
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Alcohols – Chemistry LibreTexts