Alencar, Poliana O. Cavalcante published the artcileA novel antioxidant sulfated polysaccharide from the algae Gracilaria caudata: In vitro and in vivo activities, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Gracilaria sulfated polysaccharide antioxidant activity oxidative stress.
Marine red macroalgae are natural sources of sulfated polysaccharides, water-binding mols. used in the food industry as thickeners, stabilizers and gelling agents. Sulfated polysaccharides extracted from the red seaweed Gracilaria caudata also show biol. activities with potential therapeutic effects against diseases associated with oxidative stress; hence, it is possible that they may be used as nutraceuticals and/or food additives. This study aimed to obtain the sulfated polysaccharides from G. caudata (SP-Gc) through enzymic extraction and to determine their chem. structure and antioxidant potential. Inductively Coupled Plasma-Optical Emission Spectrometry showed that SP-Gc have 0.9% of sulfur atoms and a degree of sulfation of 0.14%. An average mol. mass of 116.51 kDa was determined through gel permeation chromatog. The SP-Gc structure as an agar-type galactan was determined by Fourier transform IR (FTIR) spectroscopy and NMR (NMR) spectroscopy (13C and 1H). The in vitro antioxidant activity of SP-Gc was determined through the following tests: ferrous ion chelating ability and total antioxidant capacity. The results indicated that SP-Gc have significant antioxidant activity in a concentration-dependent manner. The in vivo antioxidant activity of SP-Gc was evaluated in an oxidative stress model induced by 2,2′-azobis(2-methylpropionamidine) dihydrochloride (ABAP) in rats pretreated with SP-Gc (3 and 10 mg/kg). Catalase (CAT) and superoxide dismutase (SOD) levels were measured and all doses increased CAT and SOD activity. These results demonstrate that SP-Gc may be used as hydrocolloids, due to their characterization as agar, and as nutraceuticals, due to their antioxidant activity.
Food Hydrocolloids published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.
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