Zhu, Minqian published the artcileStructural characterization and immunological activity of pectin polysaccharide from kiwano (Cucumis metuliferus) peels, Application In Synthesis of 59-23-4, the main research area is Cucumis peel macrophage immunol pectin polysaccharide; Immunological activity; Kiwano (Cucumis metuliferus) peels; Pectin polysaccharide; Structural characterization.
Two novel polysaccharides, namely CMPP-1 and CMPP-2, from kiwano (Cucumis metuliferus) peels were isolated through hot-water extraction, followed by ethanol precipitation and column chromatog. The results showed that CMPP-1 and CMPP-2 were hetero-galacturonans with different mol. weights of 7.35 kDa and 6.90 kDa, resp. Both of CMPP-1 and CMPP-2 were mainly composed of glucuronic acid (45.93% and 51.75%, resp.), and other monosaccharides including rhamnose, arabinose, galactose, glucose, xylose, fucose, mannose, galacturonic acid, and mannuronic acid. The results of structural characterization from FT-IR and NMR confirmed that CMPP-1 and CMPP-2 were pectin with highly branched structure. Furthermore, both CMPP-1 and CMPP-2 possessed immune-enhancing activity and could enhance the secretion of nitric oxide and cytokines (TNF-α, IL-6) in a dose-dependent manner. Especially, CMPP-1 had higher immune activity than CMPP-2 as the min. effective concentration were 0.78μg/mL and 6.25μg/mL, resp. These findings provide a scientific basis for further utilization of polysaccharide from kiwano peels.
Carbohydrate Polymers published new progress about Cucumis metuliferus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.
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