Yang, Xiaolong published the artcileA neutral polysaccharide with a triple helix structure from ginger: Characterization and immunomodulatory activity, COA of Formula: C6H12O6, the main research area is polysaccharide ginger immunomodulator triple helix structure; Ginger polysaccharide; Immunomodulatory activity; Structure characterization; Triple helix structure; α-(1→4)-glucan.
A neutral ginger polysaccharide fraction (NGP) was isolated from ginger, and its primary structures and immunomodulatory activity were investigated. The results showed that NGP had a low mol. weight of 6305 Da. NGP principally consisted of glucose (93.88%) together with minor levels of galactose (3.27%) and arabinose (1.67%). Besides, results of methylation anal. and 1D/2D NMR spectroscopy demonstrated that NGP was α-glucan which had the main chain of 1,4-linked α-D-Glcp and α-D-Glcp residues branched at C-6 position which was different from the common triple helical β-glucans. NGP also displayed a remarkable immunol. activity on the RAW264.7 cells in vitro. It could significantly enhance the proliferation of macrophages without cytotoxicity and increase the production of immune substances (NO, TNF-α, IL-1β and IL-6). The secretion at the concentration of 200μg/mL was 29.41μM, 1496.71, 44.30 and 1889.83 pg/mL for each substance, resp. The results indicated that NGP could be a potential immune agent and might provide meaningful information for further chain conformation and immune mechanism research.
Food Chemistry published new progress about Cell proliferation. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts