Maculewicz, Jakub published the artcileIn vitro methods for predicting the bioconcentration of xenobiotics in aquatic organisms, Category: alcohols-buliding-blocks, the main research area is vitro method bioconcentration xenobiotic aquatic organism; Bioaccumulation; Bioconcentration; Membrane partitioning; Protein binding; Sorption.
The accumulation of anthropogenic chem. substances in aquatic organisms is an immensely important issue from the point of view of environmental protection. In the context of the increasing number and variety of compounds that may potentially enter the environment, there is a need for efficient and reliable solutions to assess the risks. However, the classic approach of testing with fish or other animals is not sufficient. Due to very high costs, significant time and labour intensity, as well as ethical concerns, in vivo methods need to be replaced by new laboratory-based tools. So far, many models have been developed to estimate the bioconcentration potential of chems. However, most of them are not sufficiently reliable and their predictions are based on limited input data, often obtained with doubtful quality. The octanol-water partition coefficient is still often used as the main laboratory tool for estimating bioconcentration However, according to current knowledge, this method can lead to very unreliable results, both for neutral species and, above all, for ionic compounds It is therefore essential to start using new, more advanced and credible solutions on a large scale. Over the last years, many in vitro methods have been newly developed or improved, allowing for a much more adequate estimation of the bioconcentration potential. Therefore, the aim of this work was to review the most recent laboratory methods for assessing the bioconcentration potential and to evaluate their applicability in further research.
Science of the Total Environment published new progress about Benthic organisms. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts