Bulat, Elif published the artcileNi(II) complexes with 1,3,2,4-dithiadiphosphetane 2,4-disulfide-based ligands: Structural insights, theoretical studies, and anticancer activities, COA of Formula: C5H12O, the main research area is nickel dimethoxyphenyl dithiadiphosphetane disulfide complex preparation crystal mol structure; anticancer activity mol structure calculation dithiadiphosphetane disulfide nickel complex.
The first synthesis of 2,4-bis(3,4-dimethoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (SAV-A1 reagent) was achieved. Seven oxo-alkyl esters (HLn) were synthesized thereof. Ni(II) complexes ([Ni(Ln)2]) of these ligands were prepared in ethanol. The structures were identified by spectral studies. Ni(II) complexes were unambiguously determined by x-ray crystallog. In addition, the ligands and their Ni(II) complexes were tested on two different human cancer cell lines, including liver and colon. Moreover, d. functional theory (DFT) calculations of the Ni(II) complexes were performed, and the mol. docking studies of these compounds with liver cancer protein, PDB ID: 3WZE and colon cancer antigen proteins, ID 2HQ6 were presented to investigate and predict potential interactions. P4S10.
Applied Organometallic Chemistry published new progress about Antitumor agents. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, COA of Formula: C5H12O.
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