Yang, Man published the artcileExtracellular vesicle glucose transporter-1 and glycan features in monocyte-endothelial inflammatory interactions, COA of Formula: C6H12O6, the main research area is endothelial cell inflammation monocyte extracellular vesicles GLUT1 glycan; Exosome; Extracellular vesicle; Glucose transporter-1; Glycan node analysis; Inflammation.
Monocyte-induced endothelial cell inflammation is associated with multiple pathol. conditions, and extracellular vesicles (EVs) are essential nanosized components of intercellular communication. EVs derived from endotoxin-stimulated monocytes were previously shown to carry pro-inflammatory proteins and RNAs. The role of glucose transporter-1 (GLUT-1) and glycan features in monocyte-derived EV-induced endothelial cell inflammation remains largely unexplored. This study demonstrates that EVs derived from endotoxin-stimulated monocytes activate inflammatory pathways in endothelial cells, which are partially attributed to GLUT-1. Alterations in glycan features and increased levels of GLUT-1 were observed in EVs derived from endotoxin-stimulated monocytes. Notably, inhibition of EV-associated GLUT-1, through the use of fasentin, suppressed EV-induced inflammatory cytokines in recipient endothelial cells.
Nanomedicine (New York, NY, United States) published new progress about Annexin V Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.
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