Wang, Yuanze published the artcileDiverse Isoquinoline Scaffolds by Ugi/Pomeranz-Fritsch and Ugi/Schlittler-Mueller Reactions, Quality Control of 22483-09-6, the main research area is isoquinoline scaffold preparation Ugi Pomeranz Fritsch Schlittler Mueller.
The Pomeranz-Fritsch reaction and its Schlittler-Mueller modification were successfully applied in the Ugi postcyclization strategy by using orthogonally protected aminoacetaldehyde di-Et acetal and complementary electron rich building blocks. Several scaffolds, including isoquinolines, carboline, alkaloid-like tetrazole-fused tetracyclic compounds, and benzo[d]azepinone scaffolds, were synthesized in generally moderate to good yield. All the authors’ syntheses provide a short MCR-based sequence to novel or otherwise difficult to access scaffolds. Hence, the authors foresee multiple applications of these synthesis technologies.
Organic Letters published new progress about Carbolines Role: SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Quality Control of 22483-09-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts