Liu, Chang’s team published research in Carbohydrate Polymers in 2021-06-01 | CAS: 59-23-4

Carbohydrate Polymers published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Liu, Chang published the artcileExtraction, characterization of aloe polysaccharides and the in-depth analysis of its prebiotic effects on mice gut microbiota, Related Products of alcohols-buliding-blocks, the main research area is aloe polysaccharide galactose rhamnose gut microbiota; Aloe polysaccharides; Gut microbiota; In-depth bioinformatics analysis; Ultrasound extraction.

Despite the well-known health benefits of aloe polysaccharide (APs), little is known about how APs modulate the gut microbiota and the relationship between microbiota and SCFAs. Here, APs was extracted by ultrasound extraction FT-IR and glycosidic linkage type anal. showed that a major part of APs consisted of → 4 -β-Manp- 1 → residues with acetyl groups. APs supplementation to mice prominently boosted SCFAs-producing Bacteroides and Parabacteria in the feces. On the other hand, it decreased the abundance of Firmicutes and Clostridium. A pos. correlation between microbiota and SCFAs was revealed, with Parabacteria and Clostridium being the key microbiota to significantly promote SCFAs. APs promoted the fructose and mannose metabolism by upregulating the gene expression of 17 enzymes, containing fructose-bisphosphate aldolase [EC:4.1.2.13]. Our findings highlight SCFAs-producing Parabacteria were primary degrader of APs, and APs may have prebiotic effects on gut microbiota.

Carbohydrate Polymers published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts