Hadian, Mojgan published the artcileSustainability by design: automated nanoscale 2,3,4-trisubstituted quinazoline diversity, Safety of 2,2-Dimethoxyethanamine, the main research area is formyl acid preparation amine isocyanide Ugi reaction; amido carboxyquinazoline preparation.
The synthetic execution of a newly designed quinazoline reaction towards a transformative sustainability in chem. was exemplified. This included nanoscale synthesis, deep chem. space exploration, scalability over 6 orders of magnitude from milligram up to 10-g resynthesis of quinazolines enabled by the simultaneous variation of four classes of building blocks. Benefits of our approach include a simple to perform, one-step procedure, mild reaction conditions and access to a very large chem. space through accessing many available building blocks. More than thousand derivatives were produced in an automated fashion on a nanoscale using pos. pressure facilitated dispensing. Along with these advantages, there is a considerable reduction in synthetic effort, reagents, solvent, glass and plastic consumables and power consumption to decrease the footprint of synthetic chem.
Green Chemistry published new progress about Amides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Safety of 2,2-Dimethoxyethanamine.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts