Gu, Ai-Ling published the artcileHighly Efficient Conversion of Propargylic Alcohols and Propargylic Amines with CO2 Activated by Noble-Metal-Free Catalyst Cu2O@ZIF-8, Product Details of C8H14O, the main research area is alkylidene cyclic carbonate oxazolidinone preparation; propargylic alc amine carbon dioxide cycloaddition; metalorganic framework ZIF8 encapsulated cuprous oxide nanoparticle preparation catalyst; CO2; Metal-Organic Frameworks; Noble-Metal-Free; Propargylic Alcohols; Propargylic Amines.
The cyclization reactions of propargylic alcs. and propargylic amines with CO2 are important in industrial applications, but it was a great challenge that non-noble-metal catalysts catalyzed both reactions under mild conditions. Herein, the catalyst Cu2O@ZIF-8 was prepared by encapsulating Cu2O nanoparticles into robust ZIF-8, and it can effectively catalyze the cyclization of both propargylic alcs. and propargylic amines with CO2 into valuable α-alkylidene cyclic carbonates and oxazolidinones with turnover numbers (TONs) of 12.1 and 19.6, which can be recycled at least five times. The mechanisms were further uncovered by NMR, FTIR, 13C isotope-labeling experiments and DFT calculations, in which Cu2O and DBU can synergistically activate the C≃C bond and the hydroxy/amino group of substrates. Importantly, it is the first example of a noble-metal-free catalyst that can catalyze both propargylic alcs. and propargylic amines with CO2 simultaneously.
Angewandte Chemie, International Edition published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Product Details of C8H14O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts