Ghandi, Mehdi published the artcileA combined multicomponent-acid catalyzed cyclization reaction as an efficient route to novel tricyclic pyrrolo[2,1-a]isoquinoline derivatives, SDS of cas: 22483-09-6, the main research area is tricyclic pyrroloisoquinoline preparation; polysubstituted pyrrole preparation heterocyclization sulfuric acid catalyst; arylglyoxal cyclic dicarbonyl dimethoxyethanamine keto ester four component Knoevenagel.
A simple, new two-step procedure for the synthesis of novel tricyclic pyrrolo[2,1-a]isoquinoline derivatives I (R = H, Me, Cl, Ph; R1 = 2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl, 2-hydroxy-6-oxocyclohex-1-en-1-yl, 4-hydroxy-2-oxo-2H-chromen-3-yl; R2 = Me, Et) is described. The initially prepared polysubstituted pyrroles II via the four-component condensation of arylglyoxals 4-RC6H4C(O)CHO, cyclic 1,3-dicarbonyls such as 1,3-cyclohexanedione, 5,5-dimethyl-1,3-cyclohexanedione, 4-hydroxy-2H-chromen-2-one, aminoacetaldehyde di-Me acetal and β-keto esters R2OC(O)CH2C(O)CH3 subsequently underwent intramol. acid-catalyzed cyclization to give the desired products in moderate to good yields I.
Journal of Heterocyclic Chemistry published new progress about Cyclic diketones Role: RCT (Reactant), RACT (Reactant or Reagent). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, SDS of cas: 22483-09-6.
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