Conte, Federica published the artcileGalactose in human metabolism, glycosylation and congenital metabolic diseases: Time for a closer look, Category: alcohols-buliding-blocks, the main research area is review galactose human metabolism glycosylation congenital metabolic disease; Collagen glycosylation; Congenital disorders of glycosylation; Galactose; Galactosemia; Keratan sulfate; Lysosomal disorders.
Galactose is an essential carbohydrate for cellular metabolism, as it contributes to energy production and storage in several human tissues while also being a precursor for glycosylation. Galactosylated glycoconjugates, such as glycoproteins, keratan sulfate-containing proteoglycans and glycolipids, exert a plethora of biol. functions, including structural support, cellular adhesion, intracellular signaling and many more. The biol. relevance of galactose is further entailed by the number of pathogenic conditions consequent to defects in galactosylation and galactose homeostasis. The growing number of rare congenital disorders involving galactose along with its recent therapeutical applications are drawing increasing attention to galactose metabolism In this review, we aim to draw a comprehensive overview of the biol. functions of galactose in human cells, including its metabolism and its role in glycosylation, and to provide a systematic description of all known congenital metabolic disorders resulting from alterations of its homeostasis.
Biochimica et Biophysica Acta, General Subjects published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts