Liu, Ying published the artcileEffects of freeze drying and hot-air drying on the physicochemical properties and bioactivities of polysaccharides from Lentinula edodes, Application In Synthesis of 59-23-4, the main research area is freeze hot air drying polysaccharide Lentinula edodes; Characterization; Drying; Immunomodulatory; Lentinula edodes; Polysaccharides.
Fresh Lentinula edodes were dried using two process technologies-freeze drying (FD) and hot-air drying (HD). The physicochem., antioxidant and immunomodulatory properties of purified polysaccharides from dried L. edodes (LEP) were then comparatively investigated. Two neutral polysaccharides (FLEP-1 and HLEP-1) and two acidic polysaccharides (FLEP-2 and HLEP-2) were obtained by DEAE-52 cellulose column. The HD treated LEP had higher levels of uronic acid than that of the FD treated LEP. The molar ratios of monosaccharides in FLEP-1, FLEP-2, HLEP-1 and HLEP-2 were different. Moreover, HD treated LEP had more galactose and less glucose. The (1 → 3)-α-glucan structure was dominant in the two neutral polysaccharides, whereas the (1 → 6)-β-glucan was dominant in the two acidic polysaccharides. Hot-air drying could thus promote the α-configuration in neutral polysaccharides while reducing the β-configuration in acidic polysaccharides. FLEP-1, FLEP-2, HLEP-1 and HLEP-2 had potential scavenging capacity against the ABTS·+, whereas freeze-dried polysaccharides exhibited a stronger scavenging ability than that of hot-air dried polysaccharide. LEP could improve immunity by inducing the secretions of NO, TNF-α and IL-6, whereas hot-air drying improved the immunomodulatory activity of LEP. Our results suggested that freeze drying and hot air drying could be appropriately used to obtain functional polysaccharides from L. edodes.
International Journal of Biological Macromolecules published new progress about Acidic polysaccharides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (HLEP-2). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.
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