Kuznetsova, E. A. published the artcileDiastereoselective intramolecular cyclization/Povarov reaction cascade for the one-pot synthesis of polycyclic quinolines, Recommanded Product: 2,2-Dimethoxyethanamine, the main research area is diimidazoquinoline diimidazolone preparation one pot regioselective diastereoselective; aryl urea intramol cyclization Povarov reaction imidazolone oxoimidazolium.
The method for the synthesis of complex alkaloid-like aza-heterocycles has been developed through the Povarov reaction of in situ generated 2-oxoimidazolium cations. The reaction leads to the formation of 2 C-N, 2 C-C bonds and three stereocenters, and features excellent regio- and diastereoselectivity. Based on the controlled experiments and quantum chem. data, the mechanism of the reaction cyclization was proposed and diastereoselectivity origins were rationalized. Addnl., a straightforward synthesis of hardly accessible 4,4′-bi(imidazol-2-one) derivatives has been achieved using the same methodol.
Organic & Biomolecular Chemistry published new progress about Cyclization, stereoselective. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Recommanded Product: 2,2-Dimethoxyethanamine.
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