Karlinskii, Bogdan Ya. published the artcileSynthesis of 2-Azidomethyl-5-ethynylfuran: A New Bio-Derived Self-Clickable Building Block, Computed Properties of 107-54-0, the main research area is azidomethylfurancarboxaldehyde preparation azide alkyne cycloaddition; triazolylmethylfurancarboxaldehyde preparation; azidomethylethynylfuran preparation polymerization copper catalyzed azide alkyne cycloaddition; biomass derived azide containing alkyne preparation polymerization; safety toxicity sodium azide.
Furanylmethyl azide I was prepared in three steps from D-fructose or cellulose; copper-catalyzed azide-alkyne cycloaddition of I with terminal alkynes and diynes yielded triazolylmethylfurancarboxaldehydes such as II [R = Me2C(OH), Ph, BuCH2, BuCH2CCCH2, MeO2C, NC(CH2)3, HO(CH2)4, BocNHCH2, HOCH2, 3-quinolinyl, MeOCH2, t-Bu, cyclopropyl, i-PrCH2CMe(OH), t-BuCMe(OH)]. 2-Azidomethyl-5-ethynylfuran III was prepared as a monomer; in the presence of CuBr and pentamethyldiethylenetriamine, it underwent polymerization to form oligomer with MN = 4100 g/mol. Sodium azide is toxic and should be handled with care.
Synthesis published new progress about Azide-alkyne 1,3-dipolar cycloaddition reaction. 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Computed Properties of 107-54-0.
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