Cabal, Luis Felipe Rodriguez published the artcileDetermination of ring-substituted amphetamines through automated online hollow fiber liquid-phase microextraction-liquid chromatography, Application of n-Octanol, the main research area is forensic ring substituted amphetamine hollow liquid microextraction chromatog; Automation; Liquid chromatography; Mass spectrometry; Microextraction; Sample preparation.
The present paper describes an original method for the online preconcentration and anal. of ring-substituted amphetamines in urine samples, used on the integration of robot-assisted hollow fiber liquid-phase microextraction (HF-LPME), high-performance liquid chromatog. (HPLC), and fluorescence detection (FLD). A laboratory-made autosampler, actuating a 100-μL syringe and equipped with a three-way solenoid microvalve, allowed the acceptor phase to flow through and be withdrawn from the lumen fiber, enabling the automated online transference of the enriched acceptor phase for chromatog. anal., through a six-port switching valve. The developed online HF-LPME-LC/FLD method demonstrated high anal. throughput and confidence, facilitating the efficient extraction and determination of the target analytes, with minimal solvent consumption and sample manipulation, in a straightforward way. Sample cleanup, analyte uptake, and anal. were carried out in 14.5 min. Under optimal conditions, automated online HF-LPME showed excellent linearity, precision, and trueness, obtaining intraday RSDs between 2.9 and 9.2% (n = 6) and interday RSDs between 5.3 and 9.3% (n = 6). Enrichment factors (EFs) ranged between 14.2 and 15.7, extraction recoveries (ERs) ranged between 17.7 and 19.5%, and the limits of detection (S/N = 3) were 2.0, 3.0, and 3.0 μg L-1 for MDA, MDMA, and MDEA, resp. The method proved to be an effortless, rapid, reliable, and environment-friendly approach for the determination of drug abuse in urine samples.
Analytical and Bioanalytical Chemistry published new progress about Automated analysis. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts