Bandini, Marco published the artcileAn effective and useful synthesis of enantiomerically enriched arylglycinols, Product Details of C8H9BrO2, the main research area is enantiomerically enriched arylglycinol preparation; amino alc chiral preparation.
A two-step synthesis of racemic arylglycinols, together with a simple and straightforward methodol. for their resolution, is described. This method constitutes a practical means of preparing racemic and optically pure electron-rich or electron-poor substituted arylglycinols, useful building blocks for the synthesis of biol. active mols. and chiral ligands. All of the chiral β-amino alcs. were isolated in good chem. yields and with excellent enantiomeric excesses. Chiral fluoroarom. vicinal amino alcs. can also be obtained with good enantiopurity using such a procedure. The key step of the strategy presented is an easy chromatog. separation of the diastereoisomeric amides prepared from acetyl mandeloyl chloride. The absolute configuration of the perfluorinated amino alcs. was determined by X-ray anal. of the corresponding amide.
European Journal of Organic Chemistry published new progress about. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Product Details of C8H9BrO2.
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