Chu, Weiwei published the artcileEffects of Xuebijing injection combined with ambroxol hydrochloride in the treatment of elderly patients with severe pneumonia on serum DAO, D-Lac, ET levels and arterial blood gas, Application In Synthesis of 23828-92-4, the publication is Guizhou Yiyao (2021), 45(10), 1525-1527, database is CAplus.
Objective To investigate the effect of Xuebijing injection combined with ambroxol hydrochloride in the treatment of elderly patients with severe pneumonia on serum DAO, D-Lac, ET levels and arterial blood gas. Methods A total of 118 elderly patients with severe pneumonia admitted to the department of respiratory medicine of our hospital were selected and divided into the control group and the observation group by random numbers table method, with 59 cases in each group. Both groups were treated with conventional treatment, the control group was given ambroxol hydrochloride on the basis of conventional treatment, and the observation group was given Xuebijing injection on the basis of the control group. Both groups were treated for 14 d. Arterial blood gas, T lymphocyte subsets, intestinal mucosal barrier function and respiratory mechanics indexes were compared between the two groups before and after treatment. Results After treatment, the levels of SaO2, PaO2, CD3+, CD4+, CD4+/CD8+ in whole blood of the observation group were higher than before treatment, and the observation group were higher than the control group (P<0.05); Pplat, PIP, mRaw, Paw, PaCO2, whole blood CD8+, serum DAO, D-Lac and ET levels were lower than before treatment, the observation group were lower than the control group (P<0.05). Conclusion Xuebijing injection combined with ambroxol hydrochloride in the treatment of elderly patients with severe pneumonia can reduce serum DAO, D-Lac, ET levels, improve intestinal mucosal barrier function and arterial blood gas, respiratory mechanics indexes, with accurately effect.
Guizhou Yiyao published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C13H19Br2ClN2O, Application In Synthesis of 23828-92-4.
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