Brufani, Mario published the artcileSynthesis of phenothiazine derivatives as potential inhibitors of phospholipase C, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Farmaco (1992), 47(5), 585-97, database is CAplus and MEDLINE.
In order to study the structure-activity relationships of phenothiazine derivatives (I, e.g., R = H, Cl, or CF3, NHR1R2 = Me2NH, EtNH2, morpholino, methylpiperazino, dicyclohexylamino) inhibiting phosphatidylinositol-specific phospholipase C (PI-PLC), the synthesis of some phenothiazine amide, amine and ester derivatives was performed mainly by reacting 10H-phenothiazine-10-propanoyl chloride with some amines and alcs.; the resulting amides were reduced with borane to yield the corresponding amines. Starting from 2-chloro and 2-trifluoromethyl-10H-phenothiazine-10-propanoyl chloride two amides were synthesized. The inhibiting activity on PI-PLC from human platelets is reported. Structure-activity relations are discussed.
Farmaco published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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