Aubineau, Thomas published the artcileA One-Pot Reaction toward the Diastereoselective Synthesis of Substituted Morpholines, SDS of cas: 96-20-8, the publication is Organic Letters (2018), 20(23), 7419-7423, database is CAplus and MEDLINE.
The diastereoselective synthesis of various substituted morpholines has been achieved from vinyloxiranes and amino-alcs. under sequential Pd(0)-catalyzed Tsuji-Trost/Fe(III)-catalyzed heterocyclization. Using the same strategy, 2,6-, 2,5-, and 2,3-disubstituted as well as 2,5,6- and 2,3,5-trisubstituted morpholines were obtained in good to excellent yields and diastereoselectivities.
Organic Letters published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, SDS of cas: 96-20-8.
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