Warshaw, Erin M. published the artcilePatch Testing to Ethylhexylglycerin: The North American Contact Dermatitis Group Experience, 2013-2018, COA of Formula: C11H24O3, the publication is Dermatitis (2022), 33(1), 36-41, database is CAplus and MEDLINE.
Ethylhexylglycerin (EHG) is a recently recognized contact allergen. The aims of the study were to characterize individuals with pos. patch test reactions to EHG and to analyze reaction strength, clin. relevance, and allergen sources. This study was a retrospective anal. of the patients patch tested to EHG (5petrolatum) by the North American Contact Dermatitis Group (2013-2018). Of 15,560 patients tested to EHG, 39 (0.25) had pos. (final interpretation of “allergic”) reactions. Most were female (71.8) and/or older than 40 years (76.9). There were no statistically significant differences between age, sex, or atopic history when compared with EHG-neg. patients. The most common anat. sites of dermatitis were the face (28.2) and scattered generalized distribution (25.6). Most EHG-pos. reactions were + (35.9) or ++ (33.3). Current clin. relevance was high (79.5); none, however, were related to occupation. Personal care products were the most common source of exposure to EHG (59.0). Ethylhexylglycerin is a rare contact allergen; the pos. frequency of 0.25is similar to other low allergenic preservatives including parabens, benzyl alc., and phenoxyethanol. The patch test concentration of 5.0seems to be nonirritating. Although relatively uncommon, EHG reactions were usually clin. relevant (79.5), often because of moisturizers/lotions/creams.
Dermatitis published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C17H20ClN3, COA of Formula: C11H24O3.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts