Leal-Duaso, A. published the artcileSynthesis of 3-alkoxypropan-1,2-diols from glycidol: experimental and theoretical studies for the optimization of the synthesis of glycerol derived solvents, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Green Chemistry (2017), 19(17), 4176-4185, database is CAplus.
A straightforward and green synthetic methodol. was derived for the synthesis of glycerol monoethers ROCH2CH(OH)CH2OH [R = Me, Et, i-Pr, etc.] from glycidol and alcs. Several homogeneous and heterogeneous basic catalysts were tested, the best results being obtained with readily available and inexpensive alk. metal hydroxides. In the best case, good yield of the desired monoether was obtained under smooth reaction conditions always with total conversion of glycidol. The selectivity of the reactions mainly depended on the alc. used, due to the concurrence of undesired side reactions. A mechanistic study carried out through computational DFT calculations, in which solvent effects were taken into account, also complemented the experiments and allowed to identify the main reaction paths taking place under reaction conditions, giving insights into the main causes affecting the reaction selectivity and also into how it could be improved.
Green Chemistry published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.
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