Coordination mode and reactivity of nickel(II) with vitamin B6 was written by Chylewska, Agnieszka;Ogryzek, Malgorzata;Halasa, Rafal;Dabrowska, Aleksandra;Chmurzynski, Lech;Makowski, Mariusz. And the article was included in Journal of Coordination Chemistry in 2014.Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
This contribution presents a selection of results obtained using spectrophotometric and potentiometric titrations For several reasons, the studied equilibrium present particular challenges to traditional anal. techniques. Equilibrium constants and UV-visible absorption spectra for different ligands in the complexation process of Ni(II) with pyridoxamine (pm), pyridoxal (pl) and pyridoxine are reported. The gradual and cumulative stability constants occurring in aqueous solution are presented for all complexes studied. Addnl., crystal-field parameters were calculated for two nickel(II) complexes synthesized, [Ni(pm)2]Cl2 (1) and [Ni(pl)2]Cl2 (2), resp. The min. inhibitory concentration and minimal bactericidal/fungicidal concentration values for Ni(II) complexes studied were obtained at 25° for 24-48 h. The activity data show that the complexes are more potent antimicrobials than the parent ligands. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts