Anticonvulsant activity of carbamate esters of certain 2,2-disubstituted 1,3-propanediols was written by Berger, F. M.. And the article was included in Journal of Pharmacology and Experimental Therapeutics in 1952.Reference of 115-84-4 The following contents are mentioned in the article:
cf. C.A. 45, 265a; 46, 1651d. The intensity and duration of the anticonvulsant action against electroshock seizures in mice were determined for the 2,2-disubstituted dimethyl, methylethyl, methylisopropyl, diethyl, ethylbutyl, ethylphenyl, dipropyl, and diphenyl derivatives of 1,3-propanediol. The diols and their monocarbamates were short-acting and weak. The dicarbamates showed a longer and stronger anticonvulsant action. The cyclic carbonate esters, which may also be called 5,5-disubstituted 1,3-dioxan-2-one derivatives, showed a weak and transient anticonvulsant action. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Reference of 115-84-4).
2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 115-84-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts