One-pot synthesis, structural characterization, UV-Vis and electrochemical analyses of new Schiff base complexes of Fe(III), Ni(II) and Cu(II) was written by Back, Davi Fernando;Manzoni de Oliveira, Gelson;Fontana, Liniquer Andre;Ramao, Brenda Fiorin;Roman, Daiane;Iglesias, Bernardo Almeida. And the article was included in Journal of Molecular Structure in 2015.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
[Ni(Pyr2tetam-2H)]·2H2O (1) (Pyr2tetam = (pyridoxyl)2-N1,N4-triethylenetetramine), [Fe(Pyr2tetam-2H)](ClO4)·H2O (2) and [Cu(Pyrtetam-H)](ClO4) (3) (Pyrtetam = pyridoxyl-N1-triethylenetetramine) were obtained through one pot reactions of triethylenetetramine, pyridoxal hydrochloride, triethylamine and the metal salts Ni(ClO4)2·6H2O, Fe(ClO4)2·6H2O and Cu(ClO4)2·6H2O. In complexes 1 and 2 the metal centers present a distorted octahedral coordination, while complex 3 shows a square pyramidal configuration. The structures were characterized through x-ray diffractometry, IR and UV-visible spectra. Cyclic voltammograms of the title compounds are also presented and discussed. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts