Zhao, Huifang et al. published their research in Journal of Agricultural and Food Chemistry in 2022 | CAS: 29106-49-8

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Safety of (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol

Time-Course Comparative Metabolome Analysis of Different Barley Varieties during Malting was written by Zhao, Huifang;Liu, Yang;Huang, Yuqing;Liang, Qiyu;Cai, Shengguan;Zhang, Guoping. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Safety of (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol The following contents are mentioned in the article:

Malt production is one of the important uses of barley, and its quality differs greatly depending on the barley varieties used. In this study, ultraperformance liquid chromatog. coupled to quadrupole time-of-flight mass spectrometry technol. was used to investigate the temporal changes of metabolites during malting in two barley varieties: Franklin (malt barley) and Yerong (non-malt barley). Also, differences in metabolite profiles were compared in the kilned malt between two other malt barley varieties (Copeland and Planet) and two non-malt varieties (ZD10 and Hua30). Results showed that degradation of trisaccharide and accumulation of UDP-glucose and mannose-1-phosphate are the key metabolic events during steeping, with Franklin showing earlier and greater changes. Earlier increase of sugars and amino acids in Franklin is associated with its faster germination rate. Comparative metabolome anal. of kilned malt from the different barley varieties indicated that malt barley accumulated more sugars, hordatine-glucoside, and oxoproline, and non-malt barley accumulated more polyphenols and monogalactosylmonoacylglycerol. These results improved the understanding of the genotypic difference in the formation of malt quality at the metabolomic level. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Safety of (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Safety of (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts