Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area was written by Velarde, Michael C.;Chan, Alison Faye O.;Sajo, Ma Easter Joy V.;Zakharevich, Igor;Melamed, Jonathan;Uy, Gemma Leonora B.;Teves, Joji Marie Y.;Corachea, Allen Joy M.;Valparaiso, Apple P.;Macalindong, Shiela S.;Cabaluna, Nelson D.;Dofitas, Rodney B.;Giudice, Linda C.;Gerona, Roy R.. And the article was included in Chemosphere in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:
Several studies have reported exposure of humans to various endocrine disrupting chems. (EDCs) worldwide. However, there is a lack of data regarding EDC exposures in humans living in Southeast Asian countries, such as the Philippines. Hence, this study measured levels of 41 EDCs in women residing in the Greater Manila Area, home to the second largest city in Southeast Asia. Urine samples from women with vs. without breast cancer were analyzed for 11 phthalate metabolites, 8 environmental phenols, and 10 bisphenols, while serum samples were analyzed for 12 perfluoroalkyl substances (PFAS). Out of the four groups of EDCs analyzed, PFAS were significantly associated with breast cancer (adjusted OR = 13.63, 95% CI: 3.24-94.88 p-trend = 0.001 for PFDoA; adjusted OR = 9.26, 95% CI 2.54-45.10, p-trend = 0.002 for PFDA; and adjusted OR = 2.66, 95% CI: 0.95-7.66, p-trend = 0.004 for PFHxA). Long-chain PFAS levels were pos. correlated with age and were significantly higher in women from Region IV-A, a heavily industrialized region, than from the National Capital Region. Overall, this study showed baseline information regarding the level of EDCs in Filipinas, providing a glimpse of EDC exposure in women living in a megalopolis city in Southeast Asia. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Electric Literature of C13H12O2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts