Manikandan, Rajendran et al. published their research in Polyhedron in 2014 | CAS: 65-22-5

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C8H10ClNO3

Synthesis, spectral characterization and crystal structure of Ni(II) pyridoxal thiosemicarbazone complexes and their recyclable catalytic application in the nitroaldol (Henry) reaction in ionic liquid media was written by Manikandan, Rajendran;Anitha, Panneerselvam;Prakash, Govindan;Vijayan, Paranthaman;Viswanathamurthi, Periasamy. And the article was included in Polyhedron in 2014.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:

The new square planar nickel(II) complexes, ([NiLPPh3]: 1, 2 and 3) were synthesized from the reaction of [NiCl2(PPh3)2] with the tridentate Schiff base ligand, pyridoxal thiosemicarbazone (L1, 4), pyridoxal N-Me thiosemicarbazone (L2, 5) and pyridoxal N-Ph thiosemicarbazone (L3, 6) resp. in ethanol. These complexes were characterized by elemental analyses, IR, UV-visible, 1H NMR, 31P NMR and ESI-MS spectroscopy. The mol. structure of the complex [Ni(L2)PPh3] (2) was determined by single-crystal x-ray diffraction, which reveals a distorted square planar geometry around the nickel(II) ion. The nitroaldol reaction was studied in detail using the nickel(II) complexes as catalysts in a homogeneous solution formed by an ionic liquid and methanol. The effect of solvent, ionic liquid, time, temperature, catalyst loading and substituent of the ligand moiety on the reaction was also studied. The β-nitroalc. products were obtained in good yields of up to 97%. A two step substrate addition mechanism was tentatively proposed based on ESI-MS spectral monitoring of the reaction mass. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts