Formation of tubules and helical ribbons by ceramide phosphoethanolamine-containing membranes was written by Inaba, Takehiko;Murate, Motohide;Tomishige, Nario;Lee, Yan-Fen;Hullin-Matsuda, Francoise;Pollet, Brigitte;Humbert, Nicolas;Mely, Yves;Sako, Yasushi;Greimel, Peter;Kobayashi, Toshihide. And the article was included in Scientific Reports in 2019.HPLC of Formula: 923-61-5 The following contents are mentioned in the article:
Ceramide phosphoethanolamine (CPE), a major sphingolipid in invertebrates, is crucial for axonal ensheathment in Drosophila. Darkfield microscopy revealed that an equimolar mixture of bovine buttermilk CPE (milk CPE) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (diC18:1 PC) tends to form tubules and helical ribbons, while pure milk CPE mainly exhibits amorphous aggregates and, at low frequency, straight needles. Neg. staining electron microscopy indicated that helixes and tubules were composed of multilayered 5-10 nm thick slab-like structures. Using different mol. species of PC and CPE, we demonstrated that the acyl chain length of CPE but not of PC is crucial for the formation of tubules and helixes in equimolar mixtures Incubation of the lipid suspensions at the resp. phase transition temperature of CPE facilitated the formation of both tubules and helixes, suggesting a dynamic lipid rearrangement during formation. Substituting diC18:1 PC with diC18:1 PE or diC18:1 PS failed to form tubules and helixes. As hydrated galactosylceramide (GalCer), a major lipid in mammalian myelin, has been reported to spontaneously form tubules and helixes, it is believed that the ensheathment of axons in mammals and Drosophila is based on similar phys. processes with different lipids. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5HPLC of Formula: 923-61-5).
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.HPLC of Formula: 923-61-5
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