Hypochlorous acid initiated lipid chlorination at air-water interface was written by Guo, Changlu;Yang, Miao;He, Jing;Kan, Guangfeng;Yu, Kai;Liu, Zhuo;Lin, Sifan;Jiang, Jie;Zhang, Hong. And the article was included in Science of the Total Environment in 2021.Related Products of 923-61-5 The following contents are mentioned in the article:
There has been a surge of interest in interfacial hypochlorous acid (HOCl) chem. for indoor air quality and public health. Here we combined nanoelectrospray mass spectrometry (nESI-MS) and acoustic levitation (AL) techniques to study the chlorination chem. of three model lipids (DPPE, POPG, DOPG) mediated by HOCl at the air-water interface of levitated water droplet. For DPPE with no C=C double bonds, HOCl was insensitive to the alkane chains, and showed considerable delay directing to head amino groups compared to that in aqueous environment. Chlorination chem., for POPG and DOPG with C=C double bonds, preferentially reacted with double bonds of one chain. The mechanism was discussed in light of these observations, and it is concluded that the increased hydrophilicity of the chlorinated chain disturbed the lipid packing and attracted it toward the water phase. In addition, the reaction rate constant and reactive uptake coefficient suggested that the chlorination of lipids exposed to HOCl at the air-water interface is likely to occur rapidly. These results gain the knowledge of HOCl mediated lipid interface reaction at the mol. level, and would better understand the adverse health effects associated with elevated indoor pollutants. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Related Products of 923-61-5).
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Related Products of 923-61-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts