New method for the determination of endocrine disrupting chemicals in Mediterranean mussel (Mytilus galloprovincialis) using ultra-high performance liquid chromatography-tandem mass spectrometry was written by Garcia-Fernandez, L.;Garcia-Corcoles, M. T.;Navalon, A.;Martin-Pozo, L.;Hidalgo, F.;Zafra-Gomez, A.. And the article was included in Microchemical Journal in 2022.Recommanded Product: 4,4′-Methylenediphenol The following contents are mentioned in the article:
There are numerous types of contaminants that pose a health risk to aquatic organisms and consequently also to humans through consumption. Endocrine disrupting compounds are found in daily-use products and have the potential to mimic natural hormones. The main objective of this work is to optimize and validate a method for the determination of bisphenols, parabens and triclocarban in natural samples of Mediterranean mussel (Mytilus galloprovincialis). The procedure involves ultrasound-assisted extraction (UAE), and a subsequent clean-up of the extracts using dispersive solid phase extraction (d-SPE) with C18 adsorbent, and anal. by ultrahigh performance liquid chromatog.-tandem mass spectrometry (UHPLC-MS/MS). Sensitivity, accuracy (trueness and precision), linearity and selectivity of the method were studied. The limits of detection ranged from 0.2 ng g-1 to 1.5 ng g-1 dry weight The trueness of the method (estimation of recovery) was between 90 % for TCC (triclocarban) and 109.6 % for BPP (bisphenol P), with an estimated precision lower than 12.6 % for all the investigated analytes. The application of the method was to specimens of Mytilus galloprovincialis collected along the Mediterranean coast of Granada (South Spain), where the species is abundant. The study conducted in different sample sites revealed EDCs presence in this aquatic species. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 4,4′-Methylenediphenol).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 4,4′-Methylenediphenol
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