Associations between urinary bisphenol A and its analogues and semen quality: A cross-sectional study among Chinese men from an infertility clinic was written by Chen, Pan-Pan;Liu, Chong;Zhang, Min;Miao, Yu;Cui, Fei-Peng;Deng, Yan-Ling;Luo, Qiong;Zeng, Jia-Yue;Shi, Tian;Lu, Ting-Ting;Yin, Wen-Jun;Lu, Wen-Qing;Yi, Gui-Lin;Qiu, Gao-Kung;Zeng, Qiang. And the article was included in Environment International in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:
Human studies on association between bisphenol A (BPA) exposure and semen quality, mostly based on single urinary measurement, are inconsistent. There is limited human evidence on BPA analogs such as bisphenol F (BPF) and bisphenol S (BPS), and little is known on potential effects of bisphenol mixtures We aimed to explore whether individual or mixtures of BPA, BPS and BPF assessed in repeated urinary measurements were associated with semen quality among 984 Chinese men from an infertility clinic. We found that higher BPA exposure was associated with increased odds ratios (ORs) of having below-reference sperm concentration, total sperm count, progressive motility and total motility (all P for trends < 0.05). Higher BPS exposure was associated with increased ORs of having below-reference progressive motility and total motility (both P for trends = 0.02); the ORs comparing extreme quartiles were 1.62 (95CI: 1.07, 2.43) and 1.57 (95CI: 1.06, 2.33), resp. Elevated risks for each outcome were also observed when bisphenol mixtures were at ≥ 55th percentiles. For semen quality parameters modeled as continuous outcomes, inverse associations with individual BPA and BPS and bisphenol mixtures were still estimated Our results suggested that higher exposure to individual BPA and BPS and bisphenol mixtures were associated with impaired semen quality. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C13H12O2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts