Synthesis of symmetric N,O-donor ligands derived from pyridoxal (vitamin B6): DFT studies and structural features of their binuclear chelate complexes with the oxofilic uranyl and vanadyl(V) cations was written by Back, Davi Fernando;Manzoni de Oliveira, Gelson;Roman, Daiane;Ballin, Marco Aurelio;Kober, Roger;Piquini, Paulo Cesar. And the article was included in Inorganica Chimica Acta in 2014.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
The synthesis and the structural characterization of sym. dimers containing uranium and vanadium atoms provide an outstanding opportunity for the study of hydrogen bonding in supramol. architectures and unusual interactions. On the search of ligands able to coordinate itself to two metal ions simultaneously, the authors synthesized the Schiff bases bis((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene) oxalohydrazide (H6Pyr2oxdihyd, 3) and bis((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene) succinohydrazide (H10pyr2sucdihyd, 4), efficient sym. ligands with an inversion center, obtained through the reaction of pyridoxine/pyridoxal hydrochloride with oxalyl dihydrazide and succinic dihydrazide. The prepared complexes are [(UO2)2(H6pyr2oxdihyd-4H+)(DMSO)4] (1) and [(VO)2(H10pyr2sucdihyd-4H+)(MeO)2] (2). Their reactions and the products obtained with the oxofilic uranyl(VI) and vanadyl(V) cations are discussed, as well as computational methods were used as complementary tools in the study of intra and intermol. bonds. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts