Zhang, Jun et al. published their research in RSC Advances in 2020 | CAS: 65-22-5

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Enhanced chemical sensing for Cu2+ based on composites of ZIF-8 with small molecules was written by Zhang, Jun;Zhao, Xiuyang;Liu, Xuefeng;Dong, Chuan. And the article was included in RSC Advances in 2020.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

Two organic mols., pyridoxal hydrazide (PAH) and salicylaldehyde based Rhodamine B hydrazone (RBS) were integrated into zeolitic imidazolate framework-8 (ZIF-8) to give composites, namely PAH/ZIF-8 and RBS/ZIF-8. The organic mols. and ZIF-8 are proposed to be assembled via hydrogen bonds and π-π stacking in the composites. The mass fraction of PAH and RBS in the composites was calculated to be 21.86% and 29.3%. The fluorescence of PAH/ZIF-8 is quenched regularly by Cu2+. The detection limit for Cu2+ was calculated to be 1.42 nM for PAH/ZIF-8, which is one order of magnitude lower than that of PAH. The detection limit for Cu2+ was determined to be 0.8 μM for RBS/ZIF-8, which is three times lower than that of RBS. The two composites both display high selectivity to Cu2+ over competing metal ions. The PAH/ZIF-8 fluorescent sensor was successfully applied to Cu2+ determination in environmental water. PAH/ZIF-8 exhibits excellent cell membrane permeability and low cytotoxicity in cellular imaging. The enhanced chem. sensor was designed by introducing small mols. into ZIF-8 for the specific recognition of Cu2+. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts