Relationship between emergent BPA-substitutes and renal and cardiovascular diseases in adult population was written by Moreno-Gomez-Toledano, Rafael. And the article was included in Environmental Pollution (Oxford, United Kingdom) in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:
Plastic waste pollution is one of the leading environmental problems of modern society. Its use, disposal, and recycling lead to the release of xenobiotic compounds such as bisphenol A (BPA), a known endocrine disruptor related to numerous pathologies. Due to the new restrictions on its use, it is gradually being replaced by derived mols., such as bisphenol F or S (BPF or BPS), whose health risks have not yet been adequately studied. In the present work, significant relationships between the new BPA substitute mols. and renal and cardiovascular diseases have been detected by performing binomial and multinomial logistic regressions in one of the worlds largest cohorts of urinary phenols. The results have shown a significant relationship between urinary BPF and renal function or heart disease (specifically congestive heart failure). Urinary BPS has shown a pos. relationship with the risk of hypertension and a neg. relationship with kidney disease. Consequently, applying new substitute mols. could imply potential health risks equivalent to BPA. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.COA of Formula: C13H12O2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts