Lao, Zhiting et al. published their research in Protein Expression and Purification in 2022 | CAS: 367-93-1

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 367-93-1

Production and characterization of GPC3-N protein and its nanobody was written by Lao, Zhiting;Li, Shuanqi;Liang, Jinhui;Su, Jingyi;Gong, Xin;Cui, Xiping;Zhao, Suqing. And the article was included in Protein Expression and Purification in 2022.Related Products of 367-93-1 The following contents are mentioned in the article:

Glypican-3 (GPC3) has a promise to be the diagnostic biomarker as well as therapeutic target for hepatocellular carcinoma (HCC). Nanobody have the great potential in clin. diagnosis and treatment for their characteristics of small size, high solubility, stability, manipulability, binding advantages, and ease of production In this study, the recombinant glypican-3-N terminal (GPC3-N) protein was expressed as inclusion body in E. coli BL21(DE3)pLysS cells and then purified, which is then used as the immunogen to construct nanobody phage library. The pos. clone (named MF15) was obtained by four rounds of bio-panning, and then transformed into the E. coil TOP10F′ cells to express nanobody protein, with the mol. weight of 19 kDa. Both Western blot and immunofluorescence anal. revealed that bacterially expressed GPC3-N protein is biol. active, and MF15 could specifically recognized native GPC3 expressed in HepG2 cells. The results in this study would provide the tech. support for the development of diagnostic kits and antibody drugs targeting GPC3. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Related Products of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts