Organotin(IV) complexes with ONS donor Schiff base ligand: synthesis, characterization and antimicrobial evaluation was written by Batra, Nisha;Malhotra, Nidhi;Assija, Sonika. And the article was included in Journal of Chemical and Pharmaceutical Research in 2014.Related Products of 65-22-5 The following contents are mentioned in the article:
Organotin(IV) complexes [R2SnL1, R2SnL2; R = Me, Et, Bu and Ph] have been synthesized by reaction of diorganodichlorotin(IV) with biol. potent Schiff base ligands 5-hydroxymethyl-4-[2-mercapto-phenylimino-methyl]-2-methyl-pyridin-3-ol H2L1, 4-[5-chloro-2-mercapto-phenylimino-methyl]-5-hydroxymethyl-2-methylpyridin-3-ol H2L2 derived from pyridoxal hydrochloride with 2-aminothiophenol and 2-amino-4-chlorothiophenol resp. The geometry of these compounds has been proposed on basis of elemental analyses, molar conductance and spectroscopic techniques IR, electronic, 1H, 13C and 119Sn NMR. On the basis of these studies it revealed that Schiff base ligands acted as ONS donor system and coordinated to tin atom in tridentate fashion with trigonal pyramidal geometry around tin atom. To compare the biopotency of these complexes, Schiff base ligands and their complexes were also tested for in vitro antimicrobial evaluation against some pathogenic fungi and bacteria. Enrichment was observed in biol. activity of ligands on coordination with tin atom. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Related Products of 65-22-5).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Related Products of 65-22-5
Referemce:
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Alcohols – Chemistry LibreTexts