Optimisation of the conditions of dispersive liquid-liquid microextraction for environmentally friendly determination of bisphenols and benzophenone in complex water matrices by LC-MS/MS was written by Coutinho, Rodrigo;Gomes Vianna, Marco Tadeu;Marques, Marcia. And the article was included in Microchemical Journal in 2022.Name: 4,4′-Methylenediphenol The following contents are mentioned in the article:
Due to well-known risks to human and environmental health, the increasing presence of several micropollutants even in very low concentrations in environmental matrixes requires sustainable and advanced anal. methods to expand monitoring programs, particularly for water quality control. The objective of this study was to optimize the conditions of the dispersive liquid-liquid microextraction (DLLME) for a combined group of emerging micropollutants (bisphenol A, bisphenol S, bisphenol F, bisphenol AF and benzophenone) in complex water matrixes. Ten variables were chosen as the most important for DLLME procedure and the Design of Experiments (DoE) approach was applied to find the most relevant variables and optimize the DLLME procedure. The optimized DLLME was then, applied to real complex water samples including raw and treated wastewaters and surface water in Rio de Janeiro city, Brazil, and the extracted samples were analyzed by ultra-performance liquid chromatog.-tandem mass spectrometry (UPLC-MS/MS). The variables vortex mixing time (VMT), Dispersive Solvent Volume (DSV) and Extractor Solvent Volume (ESV) are the most important among the variables evaluated. The recovery efficiencies ranged from 60 to 120% after optimization the amounts of target compounds found in the five real aqueous matrixes varied from 0.005 to 150μg L-1. The association of optimized DLLME with the UPLC-MS/MS met the validation requirements adopted and generated anal. results of high quality. The advantages of this extraction technique include reduction of cost per anal.; low volume of samples and low volume of solvent required; no need to use cartridges; reduction of waste generation. The method is, therefore, suitable to process large numbers of samples, particularly in countries with limited budgets for environmental monitoring. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Name: 4,4′-Methylenediphenol).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 4,4′-Methylenediphenol
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