In 2019,Green Chemistry included an article by Wei, Zheyu; Ru, Shi; Zhao, Qixin; Yu, Han; Zhang, Gang; Wei, Yongge. Category: alcohols-buliding-blocks. The article was titled 《Highly efficient and practical aerobic oxidation of alcohols by inorganic-ligand supported copper catalysis》. The information in the text is summarized as follows:
The oxidation of alcs. to aldehydes or ketones is a highly relevant conversion for the pharmaceutical and fine-chem. industries, and for biomass conversion, and is commonly performed using stoichiometric amounts of highly hazardous oxidants. The aerobic oxidation of alcs. with transition metal complex catalysts previously required complicated organic ligands and/or nitroxyl radicals as co-catalysts. Herein, we report an efficient and eco-friendly method to promote the aerobic oxidation of alcs. using an inorganic-ligand supported copper catalyst 1, (NH4)4[CuMo6O18(OH)6], with O2 (1 atm) as the sole oxidant. Catalyst 1 is synthesized directly from cheap and commonly available (NH4)6Mo7O24·4H2O and CuSO4, which consists of a pure inorganic framework built from a central CuII core supported by six MoVIO6 inorganic scaffolds. The copper catalyst 1 exhibits excellent selectivity and activity towards a wide range of substrates in the catalytic oxidation of alcs., and can avoid the use of toxic oxidants, nitroxyl radicals, and potentially air/moisture sensitive and complicated organic ligands that are not com. available. Owing to its robust inorganic framework, catalyst 1 shows good stability and reusability, and the catalytic oxidation of alcs. with catalyst 1 could be readily scaled up to gram scale with little loss of catalytic activity, demonstrating great potential of the inorganic-ligand supported Cu catalysts in catalytic chem. transformations. The experimental process involved the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Category: alcohols-buliding-blocks)
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Category: alcohols-buliding-blocks It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts